Welcome to GRK 1910
GRK 1910 is a joint Research Training Group funded by the Deutsche For-schungsgemeinschaft (DFG) focussing on the medicinal chemistry of selective GPCR ligands.
The Research Training Group is located at the Friedrich-Alexander University Erlangen-Nürnberg and the University Regensburg.
The program started on 1st October 2013.
Retreat 2016
14.07.2016
This year the retreat will be devided into two parts.
The PhD students and postdocs will meet on July 21st-22nd at Berghotel Sammüller in Neumarkt. At the same time, the PIs and coordinators meet at the Strandhotel Seehof in Langlaus
Retreat program
8th Summer School "Medicinal Chemistry"
16.06.2016
The 8th Summer School "Medicinal Chemistry" organized and presented of the GRK1910 will take place in Regensburg on 21st-23rd September 2014.
For more informtion, see: Summer School 2016
GRK1910 workshop with Kevin Burgess
27.04.2016
On June 7/8, 2016, Kevin Burgess from the Texas A&M University will give a workshop for GRK1910 members.
The workshop will start on June 7th at 2 pm and will end on June 8th at 1 pm on the campus of the University of Regensburg, Biology building, room DE 2.121.
3rd Conference on Impedance-Based Cellular Assays (IBCA2016) in Regensburg
The 3rd conference on impedance-based cellular assays will be hosted by the Universitaet Regensburg from August 9th till 12th.
More details on program and registration can be found on the conference website (http://www.ibca2016.net).
High-Class GPCR Meeting organized by GLISTEN and GRK1910
12.04.2016
As an initiative of the COST-funded GLISTEN network in collaboration with the GRK 1910 research group an outstanding group of GPCR experts from the research community and industry met in Erlangen to discuss the latest and hottest topics regarding ligand-receptor interactions, crystal structures and transmembrane signalling.
Over 170 participants had to chance to attend the talks of highly prominent speakers including Nobel laureate Brian Kobilka. Additionally, 75 posters were presented during two sessions.
see also:
8th Summer School "Medicinal Chemistry"
08.02.2016
The 8th Summer School "Medicinal Chemistry" organized and presented of the GRK1910 will take place in Regensburg on 21-23th September 2016.
For more informtion, see: Summer School 2016
GRK Seminar "Good Scientific Practice"
13.01.2016
Seminar on "Good Scientific Practice" featuring
Dr. Brian Johnson (Wiley), who gives a talk entitled "Cases and Consequences of Scientific Misconduct – A Publisher’s View",
and
Prof. Christoph Meinel (Department of Philosophy and Humanities, UR)
Date: 10.02.2016, 3.00 p.m.
Venue: UR, lecture hass H46
Workshop at Amgen Research GmbH in Regensburg
10.11.2015
A group of RTG fellows visited the high throughput screening facilities of Amgen Research GmbH in Regensburg.
According to official numbers the HTS lab screeens more than 15 million compounds per year for a variety of different targets. After an introductory talk describing Amgen's screening approaches and strategies, a tour through the HTS labs provided a vivid impression about lab automation and standardization. The day was completed by a mini-workshop on label-free approaches to monitor cell-based assays with special emphasis on GPCR as targets.
Talk Prof. Dr. Clemencia Pinilla
22.10.2015
Prof. Dr. Clemencia Pinilla (Torrey Pines Institute for Molecular Studies, San Diego) will give a talk entitled "Positional Scanning Libraries: Concepts, Identification of GPCR ligands and Elucidation of T cell specificity".
Date: 11.11.2015, 5.15 p.m.
Venue: FAU Erlangen-Nürnberg
Workshop on High Troughput Screening
14.10.2015
On Monday, November 9, GRK members will visit the High Throuput Screening facilities of Amgen (https://www.amgen.de/) in Regensburg in the morning, followed by a mini-workshop on label-free technologies in the afternoon.
On Tuesday, November 10, Dr. Clemencia Pinilla from the Torrey Pines Institute for Molecular Studies (http://www.tpims.org/our-scientists/california-team/clemencia-pinilla) will give a workshop on the use of synthetic combinatorial compound libraries for the de-novo identification of bioactive compounds, in Erlangen.
Retreat 2015: Hot scientific discussions on Schloss Thurnau
24.07.2015
At very summery temperatures above 30°C the second retreat of the Research Training Group took place on 22st-23nd July. After two great talks by Prof. Uwe Sonnewald and Prof. Torsten Kuwert the RTG members reported on their current projects, which formed the starting point for many fruitful and lively discussions.
To see some impressions of the retreat, please click on the picture below.
Talk Prof. Dr. Léon Ghosez
29.04.2015
Prof. Dr. Léon Ghosez (Institut Européen de Chimie et Biologie Bordeaux/Pessac – France) will give a talk entitled "Design and synthesis of natural-inspired scaffolds as an invaluable source of molecules of therapeutic interest".
Date: 06.05.2015, 5.15 p.m.
Venue: FAU Erlangen-Nürnberg
Date and venue confirmed for Retreat 2015
02.04.2015
We are happy to announce that the date and venue of the Retreat 2015 can now be confirmed.
The event will take place on July 22nd-23rd at Schloss Thurnau west of Bayreuth.
More information will be provided shortly.
Talk Prof. Dr. Jens Carlsson
11.03.2015
Prof. Dr. Jens Carlsson (Stockholm University) will give a talk entitled "Successes and failures in structure-based discovery of GPCR ligands: Two steps forward, one step back".
Date: 22.04.2015, 5.15 p.m.
Venue: Lecture Hall, Schuhstrasse 19, FAU Erlangen-Nürnberg
Post-doc position available
16.12.2014
The Research Training Group “Medicinal Chemistry of Selective GPCR Ligands” (GRK 1910) offers
1 Post-Doc Position (TV‐L E13, 100%)
Associated to the Laboratory of Prof. Peter Gmeiner (Chair of Pharmaceutical/Medicinal Chemistry), Friedrich-Alexander University Erlangen-Nürnberg
Summer School 2014
25.10.2014
The 7th Summer School “Medicinal Chemistry” took place from 17th-19th Sep in Regensburg. Speakers from all around the world were invited to present their latest findings in drug research, GPCR structure and function as well as anti-infectives. PhD students presented their projects by posters or short oral presentations. The dinner in the evening provided an excellent framework for fruitful scientific and non scientific discussions.
To see some impressions of the event, please click on the picture below.
Talk Dr. Mélanie Hall
20.10.2014
Dr. Mélanie Hall (Department of Chemistry, University of Graz, Austria) will give a talk on the "Development of Biocatalytic Tools for the Synthesis of Enantiopure Molecules".
Date: 29.10.2014, 5.15 p.m.
Venue: Lecture Hall H46, Organic Chemistry, University Regensburg
Retreat 2014: "What belongs together, grows together"
24.07.2014
The first retreat of the Research Training Group took place on 21st-22nd July. After two days with great talks by Prof. Roland Seifert and Prof. Joachim Hornegger, 24 progress reports of the PhD students and postdocs, and a lot lot of fruitful communication the group really welded together.
To see some impressions of the retreat, please click on the picture below.
Partnership with New International Graduate Program
21.05.2014
The GRK 1910 is proud to announce the partnership with the new international graduate program "Receptor Dynamics: Emerging Paradigms for Novel Drugs". This program is a joint initiative of the Universities of Würzburg, Bayreuth, Erlangen-Nürnberg, and Regensburg and is funded by the Elite Network of Bavaria, Germany.
The FAU Erlangen-Nürnberg and the University Regensburg offer one PhD Position each:
FAU: Irreversibly-binding GPCR ligands and slowly diffusing analogs
For more information about the graduate program and the application process, see >Receptor Dynamics: open positions<
Deadline for applications: 15 June 2014
7th Summer School "Medicinal Chemistry"
13.05.2014
The 7th Summer School "Medicinal Chemistry" organized and presented of the GRK1910 will take place in Regensburg on 17-19th September 2014.
For more informtion, see: Summer School 2014
Date and venue confirmed for Retreat 2014
05.03.2014
We are happy to announce that the date and venue of the Retreat 2014 can now be confirmed.
The event will take place on July 21st-22nd at the conference hotel Behringers next to Gößweinstein in the "Fränkische Schweiz".
1. Workshop 2014
17.02.2014
Current members of the GRK 1910 (click to enlarge)
The first workshop of our Research Training Group was held in Regensburg on February 13-14th.
Doctoral students, postdocs and supervisors met to get to know each other and to learn about all the starting research projects and teaching events. Additionally, Prof. Dr. Morten Grøtli (University of Gothenburg) gave a lecture about developing MEK and RET Inhibitors. Prof. Tim Clark introdoced the brand new web-based modeling server.
The assembly of graduates and postdocs elected Kilian Kuhn (UR) and Thorsten Schäfer (FAU) as Student representatives.
Some impressions of the workshop: (click to enter picture gallery)
Kick-off Meeting
22.11.2013
The first official event of the Research Training Group took place on November 21st. The FAU hosted the Kick-off Meeting featuring the following four invited speakers:
Prof. Dr. Rob Leurs (VU University Amsterdam)
Prof. Dr. Annette Beck-Sickinger (University Leipzig)
Prof. Dr. Christa Müller (University Bonn)
Prof. Dr. Elliott Richelson (Mayo Clinic, Jacksonville, Florida)
Pictures taken at the Kick-off Meeting: (click to enter image gallery)
